Educ. Online
Homology repair (HDR) is a natural DNA repair mechanism induced by DNA double-strand breaks (DSB). The CRISPR/Cas9 system generates DSB on the chromosome, resulting in DNA repair. In the presence of donor DNA, homologous directed repair (HDR) occurs and replaces the genetic information (insertion, removal or substitution) in the chromosome with new information from the donor DNA.
CRISPR/Cas9 PlatformCB provides a competitive price for synthesizing donor DNA sequences, cloning them into your chosen vector and performing sequence verification, regardless of the size or complexity of the vector. Our expertise and experience in highly reliable CRISPR technology applications make us a valuable partner for researchers worldwide.